Hematopoietic Stem Cell Transplantation and Cellular Therapies for Autoimmune Diseases
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- Item Code: 68323
- Author: Dominique Farge,John A. Snowden,Milton A. Ruiz,Riccardo Saccardi,Richard K. Burt
- Publisher: CRC PRESS
- Edition: 1st
- Isbn : 9781138558557
- 13 EAN: 9781138558557
This book summarizes the global progress in medical and scientific research toward converting traditionally chronic autoimmune diseases into a drug-free reversible illness using hematopoietic stem cell transplantation (HSCT) and other cellular therapies such as T regulatory cells (Treg), mesenchymal stromal/stem cells, and chimeric antigen receptor T (CAR T) cells in order to reintroduce sustained immune tolerance. This title provides information on different types of stem cells and immune cells; post-transplant immune regeneration; cellular regulatory requirements; ethical and economic considerations; and the advantages and disadvantages of HSCT in the treatment of a variety of autoimmune diseases versus current conventional treatments. Arranged by disease, the text provides a comprehensive guide to HSCT for all types of autoimmune/immune disorders including monogenetic autoimmune diseases; autoimmune aplastic anemia; neurologic immune diseases including multiple sclerosis, chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, and stiff person syndrome; rheumatologic diseases such as systemic sclerosis and systemic lupus erythematosus; dermatologic diseases such as pemphigus; gastrointestinal disorders such as Crohn’s disease and celiac disease; and immune-mediated endocrinologic disease type I diabetes mellitus. Guidance is provided on the transplantation technique, cell collection and processing, conditioning regimens, infections, and early and late complications.
| Book specification | |
|---|---|
| Author | Dominique Farge,John A. Snowden,Milton A. Ruiz,Riccardo Saccardi,Richard K. Burt |
| Publisher | CRC PRESS |
| Edition | 1st |
| Isbn | 9781138558557 |
| 13 EAN | 9781138558557 |
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